Development of ocular hypertension secondary to tamponade with light versus heavy silicone oil: A systematic review

Development of ocular hypertension secondary to tamponade with light versus heavy silicone oil: A systematic review

Blog Article

Aim: The intraocular silicone oil (SO) tamponades used in the treatment of retinal detachment (RD) have been associated with a difference ocular hypertension (OH) rate.To clarify, if Jujutsu Kaisen this complication was associated to use of standard SO (SSO) versus heavy SO (HSO), we performed a systematic review and meta-analysis of comparative study between two kind of SO (standard or light vs.heavy) for the treatment of RD and macular hole, without restriction to study design.Materials and Methods: The methodological quality of two randomized clinical trials (RCTs) were evaluated using the criteria given in the Cochrane Handbook for Systematic Reviews of Intervention, while three non-RCTs were assessed with the Newcastle-Ottawa Scale and Strengthening the Reporting of Observational Studies in Epidemiology checklists.

We calculated Mantel-Haenszel risk ratio (RR) with 95% confidence intervals (95% CIs).The primary outcome was the rate of patients with OH treated with SSO compared to HSO.Results: There were a higher number of rates of OH in HSO compared to SSO.This difference was statistically significant with the fixed effect model (Mantel-Haenszel RR; 1.

55; 95% CI, 1.06-2.28; P = 0.02) while there was not significative difference with the random effect model (Mantel-Haenszel RR; 1.

51; 95% CI, 0.98-2.33; P = 0.06).

Conclusion: We noted a trend that points out a higher OH rate in HSO group compared to SSO, but this finding, due to the small size and variable design of studies, needs Side Step Bar to be confirmed in well-designed and large size RCTs.